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Here's a quote from a paper we read for Human Behavioral Genetics:
"Population-level sequencing will provide the first truly unbiased look at 20,000 genes that have rarely been sequenced in 'normal' persons, and it will probably reveal that we understand genotype–phenotype correlations even less well than we currently suppose."
From "Genomic Medicine — An Updated Primer" -- authors: W. Gregory Feero, M.D., Ph.D., Alan E. Guttmacher, M.D., and Francis S. Collins, M.D., Ph.D.
It would be my own personal contention that we understand pretty much everything about chemical-level biology -- let alone molecular-level biology -- considerably less well than we currently suppose! Which would indicate an even greater misconception of the way those underpinnings may affect who we are...............
It seems to me that every time we turn around, we discover a whole new set of processes is going on. Things we never dreamed of................
We humans are so eager to leap to the conclusion that NOW we understand it (whatever "it" may be)!
I'm glad to see these authors recognizing the fact that we surely don't understand genotype-phenotype correlations as well as many currently suppose!
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